Ralph Mazitschek Selected Research

(7- (2- ((1,1'- biphenyl)- 4- ylmethylene)hydrazinyl)- N- hydroxy- 7- oxoheptanamide)

1/2013

Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.

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Ralph Mazitschek Research Topics

Disease

19	Neoplasms (Cancer) 01/2021 - 05/2003
8	Malaria 10/2016 - 05/2008
6	Multiple Myeloma 01/2020 - 08/2011
4	Breast Neoplasms (Breast Cancer) 08/2021 - 10/2017
3	Ovarian Neoplasms (Ovarian Cancer) 08/2011 - 11/2007
2	Sepsis (Septicemia) 11/2021 - 02/2015
2	Infections 09/2020 - 12/2006
2	Major Depressive Disorder (Major Depressive Disorders) 01/2019 - 01/2018
2	Cognitive Dysfunction 02/2016 - 01/2013
2	Starvation 05/2015 - 06/2009
2	Fibrosis (Cirrhosis) 02/2012 - 10/2011
1	Inflammation (Inflammations) 11/2021
1	COVID-19 03/2021
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Glioblastoma (Glioblastoma Multiforme) 01/2020
1	Brain Diseases (Brain Disorder) 01/2019
1	AIDS-Related Complex (ARC) 01/2018
1	Disease Progression 12/2017
1	Proteinuria 12/2017
1	Nephritis 12/2017
1	Lupus Nephritis 12/2017
1	Frontotemporal Dementia (Semantic Dementia) 07/2017
1	Aneuploidy (Aneuploid) 01/2017
1	Pain (Aches) 01/2017
1	Hyperalgesia 01/2017
1	Hypesthesia (Numbness) 01/2017
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2017
1	Central Nervous System Diseases (CNS Diseases) 02/2016
1	Obesity 05/2015
1	Weight Loss (Weight Reduction) 05/2015
1	Medulloblastoma 04/2015
1	Body Weight (Weight, Body) 04/2015
1	Shock 04/2015

Drug/Important Bio-Agent (IBA)

12	Histone Deacetylase InhibitorsIBA 11/2021 - 12/2006
9	Histone Deacetylases (Histone Deacetylase)IBA 11/2021 - 04/2008
5	Proteins (Proteins, Gene)FDA Link 03/2021 - 11/2007
5	Pharmaceutical PreparationsIBA 01/2021 - 11/2007
4	halofuginoneIBA 03/2021 - 06/2009
4	Antimalarials (Antimalarial Agents)IBA 10/2016 - 06/2009
4	Amino Acids FDA Link 05/2015 - 06/2009
3	Bortezomib (Velcade)FDA Link 10/2017 - 11/2008
3	ricolinostatIBA 01/2017 - 03/2012
3	Proteasome InhibitorsIBA 11/2016 - 11/2008
2	Growth Factor ReceptorsIBA 08/2021 - 10/2017
2	WT161IBA 08/2021 - 10/2017
2	prolyl T RNA synthetaseIBA 03/2021 - 05/2015
2	Histones (Histone)IBA 01/2021 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 01/2020 - 11/2007
2	Biological ProductsIBA 01/2020 - 10/2017
2	Histone Deacetylase 6IBA 12/2017 - 10/2017
2	TubulinIBA 12/2017 - 11/2008
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2017 - 11/2007
2	ChromatinIBA 02/2016 - 01/2013
2	febrifugineIBA 05/2015 - 02/2012
2	Vorinostat FDA Link 04/2015 - 02/2015
2	Phosphotransferases (Kinase)IBA 09/2014 - 08/2004
2	tubacinIBA 08/2011 - 06/2009
2	Protein Isoforms (Isoforms)IBA 10/2010 - 07/2010
1	ZincIBA 11/2021
1	Proline (L-Proline)FDA Link 03/2021
1	Nucleic AcidsIBA 09/2020
1	obtusaquinoneIBA 01/2020
1	histone deacetylase 3IBA 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 01/2020
1	Deoxyglucose (2 Deoxy D glucose)IBA 01/2020
1	Eicosapentaenoic AcidIBA 01/2019
1	Docosahexaenoic AcidsIBA 01/2019
1	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2019
1	tianeptine (Stablon)IBA 01/2018
1	anti-dsDNA autoantibodyIBA 12/2017
1	Immunoglobulins (Immunoglobulin)IBA 12/2017
1	CytokinesIBA 12/2017
1	Immunoglobulin G (IgG)IBA 12/2017
1	ProgranulinsIBA 07/2017
1	citarinostatIBA 01/2017
1	Cisplatin (Platino)FDA LinkGeneric 01/2017
1	platelet protein P47 (pleckstrin)IBA 01/2017
1	Lysine (L-Lysine)FDA Link 01/2017
1	azaauroneIBA 10/2016
1	Chloroquine (Aralen)FDA LinkGeneric 09/2015
1	celastrolIBA 05/2015
1	LeptinIBA 05/2015
1	Leptin ReceptorsIBA 05/2015
1	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 05/2015
1	Transfer RNA (tRNA)IBA 05/2015
1	Histone Deacetylase 2IBA 04/2015
1	LipopolysaccharidesIBA 04/2015
1	salicylhydroxamic acid (SHAM)IBA 04/2015
1	SolutionsIBA 04/2015
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 04/2015
1	Sodium Chloride FDA LinkGeneric 04/2015
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 09/2014
1	Glycogen Synthase KinasesIBA 09/2014
1	GranulinsIBA 01/2013
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2013
1	(7- (2- ((1,1'- biphenyl)- 4- ylmethylene)hydrazinyl)- N- hydroxy- 7- oxoheptanamide)IBA 01/2013

Therapy/Procedure

10	Therapeutics 01/2017 - 08/2004
2	Drug Therapy (Chemotherapy) 01/2017 - 11/2007
1	Ligation 02/2015
1	Punctures 02/2015